PBG                   package:nlme                   R Documentation

_E_f_f_e_c_t _o_f _P_h_e_n_y_l_b_i_g_u_a_n_i_d_e _o_n _B_l_o_o_d _P_r_e_s_s_u_r_e

_D_e_s_c_r_i_p_t_i_o_n:

     The 'PBG' data frame has 60 rows and 5 columns.

_F_o_r_m_a_t:

     This data frame contains the following columns:

     _d_e_l_t_a_B_P a numeric vector

     _d_o_s_e a numeric vector

     _R_u_n an ordered factor with levels 'T5' < 'T4' < 'T3' < 'T2' < 'T1'
          < 'P5' < 'P3' < 'P2' < 'P4' < 'P1'

     _T_r_e_a_t_m_e_n_t a factor with levels 'MDL 72222'  'Placebo' 

     _R_a_b_b_i_t an ordered factor with levels '5' < '3' < '2' < '4' < '1'

_D_e_t_a_i_l_s:

     Data on an experiment to examine the effect of a antagonist MDL
     72222 on the change in blood pressure experienced with increasing
     dosage of phenylbiguanide are described in Ludbrook (1994) and
     analyzed in Venables and Ripley (1999, section 8.8).  Each of five
     rabbits was exposed to increasing doses of phenylbiguanide after
     having either a placebo or the HD5-antagonist MDL 72222
     administered.

_S_o_u_r_c_e:

     Pinheiro, J. C. and Bates, D. M. (2000), _Mixed-Effects Models in
     S and S-PLUS_, Springer, New York.  (Appendix A.21)

     Venables, W. N. and Ripley, B. D. (1999) _Modern Applied
     Statistics with S-PLUS (3rd ed)_, Springer, New York.

     Ludbrook, J. (1994), Repeated measurements and multiple
     comparisons in cardiovascular research, _Cardiovascular Research_,
     *28*, 303-311.

